KEAP1 Antibody
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100
UniProt
Q14145
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
297CT6.1.6
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KEAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KEAP1 antibody is available for research use only.
Storage Conditions
Aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Pig
Image Legend
KEAP1 antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~70 kDa.
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