Skeletal Muscle Actin Antibody
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with a-actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an a-actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:500, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P68133
Host
Mouse
Reactivity
Human
Immunogen
This skeletal muscle Actin antibody was produced from a mouse immunized with ACTA1 recombinant protein.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
337CT30.10.1
Applications
WB, IHC, FACS, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the skeletal muscle Actin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This skeletal muscle Actin antibody is available for research use only.
Storage Conditions
Aliquot the skeletal muscle Actin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the skeletal muscle Actin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Chicken, Mouse, Pig, Rabbit, Rat
Image Legend
Skeletal muscle Actin antibody western blot analysis in CEM lysate.
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