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Skeletal Muscle Actin Antibody

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with a-actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an a-actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:500, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50

UniProt

P68133

Host

Mouse

Reactivity

Human

Immunogen

This skeletal muscle Actin antibody was produced from a mouse immunized with ACTA1 recombinant protein.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

337CT30.10.1

Applications

WB, IHC, FACS, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the skeletal muscle Actin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This skeletal muscle Actin antibody is available for research use only.

Storage Conditions

Aliquot the skeletal muscle Actin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the skeletal muscle Actin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Chicken, Mouse, Pig, Rabbit, Rat

Image Legend

Skeletal muscle Actin antibody western blot analysis in CEM lysate.

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