BCL-6 Antibody
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:250
UniProt
P41182
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
305CT16.3.3
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the BCL-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BCL-6 antibody is available for research use only.
Storage Conditions
Aliquot the BCL-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
BCL-6 antibody western blot analysis in NCI-H292 lysate. Predicted molecular weight: 78~100 kDa.
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
