TSC2 Antibody
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Western blot: 1:100
UniProt
P49815
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This TSC2 antibody was produced from a mouse immunized with TSC2 recombinant protein.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
249CT19.1.3
Applications
WB, IF, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TSC2 antibody is available for research use only.
Storage Conditions
Aliquot the TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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