CD44 Antibody
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:500, Immunohistochemistry (FFPE) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50
UniProt
P16070
Host
Mouse
Reactivity
Human
Immunogen
This CD44 antibody was produced from a mouse immunized with recombinant protein.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
Hermes-3
Applications
WB, IHC-P, IF, FACS
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD44 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD44 antibody is available for research use only.
Storage Conditions
Aliquot the CD44 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD44 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell surface, cytoplasmic
Image Legend
CD44 antibody western blot analysis in HeLa lysate
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