NALP12 Antibody (NLRP12)

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:1500

UniProt

P59046

Host

Mouse

Reactivity

Mouse

Immunogen

This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Clonality

Monoclonal

Isotype

IgM k

Clone

228CT4.1.3

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Store at 4oC for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NALP12 antibody is available for research use only.

Storage Conditions

Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.