RIZ1 Antibody
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, ChIP: 1:100
UniProt
Q13029
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Clonality
Monoclonal
Isotype
IgG1
Clone
33AT1045
Applications
CHIP, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the RIZ1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RIZ1 antibody is available for research use only.
Storage Conditions
Aliquot the RIZ1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the RIZ1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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