p100 Antibody (TPX2)
p100 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. [UniProt]
Product Specifications
UniProt
Q9ULW0
Host
Mouse
Immunogen
A KLH conjugated synthetic peptide from the human protein was used as immunogen for this p100 antibody.
Clonality
Monoclonal
Isotype
IgG1
Applications
WB, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the p100 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This p100 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6678847/datasheet/f40192-0.4ml.pdf
CAS Number
9007-83-4
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