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VEGF4 Antibody

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:500

UniProt

O43915

Host

Mouse

Reactivity

Human, Mouse

Immunogen

This VEGF4 antibody was produced from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.

Clonality

Monoclonal

Isotype

IgG1

Clone

28AT743.288.48

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VEGF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VEGF4 antibody is available for research use only.

Storage Conditions

Aliquot the VEGF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the VEGF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

The VEGF4 antibody used in western blot to detect VEGF4 in HDMEC cell lysate. Expected molecular weight: 40-53 kDa (pro-form), ~21 kDa (mature/active form) .

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