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VEGFC Antibody

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:500

UniProt

P49767

Host

Mouse

Reactivity

Human, Mouse

Immunogen

This monoclonal antibody was produced from mice immunized with peptides from human VEGFC.

Clonality

Monoclonal

Isotype

IgG1

Clone

30AT1174.77

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VEGFC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VEGFC antibody is available for research use only.

Storage Conditions

Aliquot the VEGFC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the VEGFC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western analysis of extracts from HDMEC cells using VEGFC antibody. Predicted molecular weight ~46 kDa.

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