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MUC20 Antibody

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50

UniProt

Q8N307

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 654-684 from the human protein was used as the immunogen for this MUC20 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, IF, FACS, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MUC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MUC20 antibody is available for research use only.

Storage Conditions

Aliquot the MUC20 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MUC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

MUC20 antibody western blot analysis in WiDr lysate.

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