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MUC20 Antibody

MUC20 may regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF) -induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Immunofluorescence: 1:10-1:50

UniProt

Q8N307

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 61-90 from the human protein was used as the immunogen for this MUC20 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the MUC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MUC20 antibody is available for research use only.

Storage Conditions

Aliquot the MUC20 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the MUC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of MUC20 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MUC20 gene (2) .

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