DSCR1 Antibody
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Product Specifications
UniProt
P53805
Host
Rabbit
Immunogen
A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DSCR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DSCR1 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6678737/datasheet/f40134-0.4ml.pdf
CAS Number
9007-83-4
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