DSCR1 Antibody
DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P53805
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 75-104 from the human protein was used as the immunogen for this DSCR1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the DSCR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DSCR1 antibody is available for research use only.
Storage Conditions
Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
DSCR1 antibody used in western blot to detect DSCR1 in endothelial cell lysate
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Frequently Asked Questions
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