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ERAB Antibody / HSD17B10

Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases; unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ERAB appears to trigger cell stress induced by the amyloid peptide.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100

UniProt

Q6IBS9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the ERAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ERAB antibody is available for research use only.

Storage Conditions

Aliquot the ERAB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Rat

Image Legend

ERAB antibody western blot analysis in 293 lysate

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