ERBB4 Antibody

ERBB4 acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q15303

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 1141-1166 from the human protein was used as the immunogen for this ERBB4 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ERBB4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ERBB4 antibody is available for research use only.

Storage Conditions

Aliquot the ERBB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ERBB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Rat

Image Legend

Western blot testing of ERBB4 antibody at 1:2000 dilution + MCF-7 lysate; Predicted molecular weight: 147-180 kDa (precursor), 120, 80 kDa (cleaved forms) .