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SUMO Antibody

Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O97102

Host

Rabbit

Reactivity

Human, Drosophila

Immunogen

A portion of amino acids 37-66 from the drome protein was used as the immunogen for this SUMO antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the SUMO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SUMO antibody is available for research use only.

Storage Conditions

Aliquot the SUMO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the SUMO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of lysate from Drosophila tissue lysate using SUMO antibody diluted at 1:1000.

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