Atibeprone
Atibeprone (Lu 53439) is a selective MAO-B inhibitor. Atibeprone has antidepressant activity[1][2].
Product Specifications
CAS Number
153420-96-3
Product Name Alternative
Lu 53439
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atibeprone.html
Smiles
O=C1OC2=C(C(C)=C1C)C=CC(OCC3=NN=C(C(C)C)S3)=C2
Molecular Formula
C17H18N2O3S
Molecular Weight
330.40
References & Citations
[1]Löscher W, et al. Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy. J Pharmacol Exp Ther. 1999 Mar;288 (3) :984-92.|[2]Chhajed M, et al. Synthesis of 5-arylidine amino-1,3,4-thiadiazol-2-[ (N-substituted benzyol) ]sulphonamides endowed with potent antioxidants and anticancer activity induces growth inhibition in HEK293, BT474 and NCI-H226 cells. Med Chem Res. 2014;23 (6) :3049-3064.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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