Human Complement C5 Deficient Heparin Plasma

<strong>Human Complement C5 Deficient Heparin Plasma</strong>_x000D_ <strong>Catalog number:</strong> B2015203_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Plasma_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20° C_x000D_ <strong>Keywords:</strong> Complement Component 5, Complement Component V, C5, CV, C5a, C5b, Complement C5, Anaphylatoxin C5a Analog, C3 and PZP-like alpha-2-Macroglobulin Domain-containing Protein 4, C5a Anaphylatoxin, CPAMD4, Prepro-C5, Complement C5 alpha'' Chain_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Burge J, Nicholson-Weller A, Austen KF. Isolation of C4-binding protein from guinea pig plasma and demonstration of its function as a control protein of the classical complement pathway C3 convertase J Immunol. 1981 Jan;126(1):232-5._x000D_ 2: Noris M, Mescia F, Remuzzi G. STEC-HUS, atypical HUS and TTP are all diseases of complement activation Nat Rev Nephrol. 2012 Nov;8(11):622-33._x000D_ 3: Shattil SJ, Cines DB, Schreiber AD. Increased fluidity of human platelet membranes during complement-mediated immune platelet injury J Clin Invest. 1978 Mar;61(3):582-9._x000D_ 4: Sanghvi SY, Schwartz RA. Leiner's disease (erythroderma desquamativum): A review and approach to therapy Dermatol Ther. 2021 Jan;34(1):e14510._x000D_ 5: Saito K, Matsumoto M. [The frontline of TMA management] Rinsho Ketsueki. 2022;63(5):463-470._x000D_ 6: Rus H, Cudrici C, Niculescu F. C5b-9 complement complex in autoimmune demyelination and multiple sclerosis: dual role in neuroinflammation and neuroprotection Ann Med. 2005;37(2):97-104._x000D_ 7: Shibata T, Cosio FG, Birmingham DJ. Complement activation induces the expression of decay-accelerating factor on human mesangial cells J Immunol. 1991 Dec 1;147(11):3901-8._x000D_ 8: Okamoto M, Yamamoto T, Matsubara S, Kukita I, Takeya M, Miyauchi Y, Kambara T. Factor XIII-dependent generation of 5th complement component(C5)-derived monocyte chemotactic factor coinciding with plasma clotting Biochim Biophys Acta. 1992 Jan 16;1138(1):53-61._x000D_ 9: Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, Bergseth G, Nymo S, Lappegård KT, Woodruff TM, Espevik T, Mollnes TE, Brekke OL. Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4 Clin Exp Immunol. 2019 Apr;196(1):97-110._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26185203">10: De Vriese AS, Sethi S, Van Praet J, Nath KA, Fervenza FC. Kidney Disease Caused by Dysregulation of the Complement Alternative Pathway: An Etiologic Approach J Am Soc Nephrol. 2015 Dec;26(12):2917-29. </a>_x000D_ _x000D_ <strong>Products Related to Human Complement C5 Deficient Heparin Plasma can be found at</strong> <a href="https://moleculardepot.com/product-category/Biofluids/"> Biofluids</a>