ONO 3708
ONO 3708 is a TXA2/PGH2 receptor antagonist that can inhibit the binding properties of U46619 in unactivated intact human platelets, with an IC50 value of 38 nM[1].
Product Specifications
CAS Number
102191-05-9
UNSPSC
12352211
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ono-3708.html
Smiles
OC(CCC/C=C\C[C@H]1[C@H](C2)C(C)([C@H]2C[C@@H]1NC([C@@H](C3CCCC3)O)=O)C)=O
Molecular Formula
C23H37NO4
Molecular Weight
391.54
References & Citations
[1]Kattelman EJ, et al. Characterization of U46619 binding in unactivated, intact human platelets and determination of binding site affinities of four TXA2/PGH2 receptor antagonists (13-APA, BM 13.177, ONO 3708 and SQ 29,548) . Thromb Res. 1986 Feb 15;41 (4) :471-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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