DHC-156
DHC-156 is a selective Brachyury small molecule downmodulator. DHC-156 can be used for chordoma research[1].
Product Specifications
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhc-156.html
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C=C2C(C=CN=C2NC3=CC(OCC(F)(F)F)=C(C=C3)F)=C1)NC(/C=C/CN(C)C)=O
Molecular Formula
C24H24F4N4O3
Molecular Weight
492.47
References & Citations
[1]Chase DH, et al. Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury. Angew Chem Int Ed Engl. 2024 Feb 13:e202316496
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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