AChRα (97-116)

AChRα (97-116), a peptide, can be used to induce experimental autoimmune myasthenia gravis (EAMG) [1]

Product Specifications

CAS Number

[663154-30-1]

UNSPSC

12352209

Target

NAChR

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/achrα-97-116.html

Purity

99.41

Solubility

DMSO : 28.57 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(NCC(N[C@H](C(N[C@H](C(O)=O)[C@@H](C)CC)=O)CC2=CN=CN2)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@@H](NC([C@H](CC(O)=O)NC(CNC([C@@H](N)CC(O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C106H162N24O30

Molecular Weight

2252.56

References & Citations

[1]Cui YZ, et al. Enhancement of T Follicular Helper Cell-Mediated Humoral Immunity Reponses During Development of Experimental Autoimmune Myasthenia Gravis. Neurosci Bull. 2019 Jun;35 (3) :507-518.