Necroptosis-IN-1

Necroptosis-IN-1, an analog of Necrostatin-1, is a potent necroptosis inhibitor. Necroptosis-IN-1 is a RIPK inhibitor[1].

Product Specifications

CAS Number

[1391980-92-9]

UNSPSC

12352005

Target

Necroptosis; RIP kinase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/necroptosis-in-1.html

Purity

98.60

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC(C(CC2=CNC3=C2C=CC=C3Cl)N1)=O

Molecular Formula

C12H10ClN3O2

Molecular Weight

263.68

References & Citations

[1]Jenny L Maki, et al. Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1. Anal Biochem. 2012 Aug 15;427 (2) :164-74.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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