Adenosine 5'-monophosphate (monohydrate)

Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2[1][2][3].

Product Specifications

CAS Number

[18422-05-4]

Product Name Alternative

5'-AMP (monohydrate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adenosine Receptor; Endogenous Metabolite; HSV

Type

Natural Products

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adenosine-5-monophosphate-monohydrate.html

Purity

99.81

Solubility

H2O : 5 mg/mL (ultrasonic; warming)

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N.O

Molecular Formula

C10H16N5O8P

Molecular Weight

365.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287 (8) :5301-9.|[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985.|[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3 (3) :161-74.