Pristimerin
Product Specifications
UNSPSC Description
Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.
Target Antigen
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Pristimerin.html
Purity
99.22
Solubility
DMF : 25 mg/mL (ultrasonic)|DMSO : 20 mg/mL (ultrasonic)
Smiles
C[C@](C1=CC=C(C(C)=C2O)C3=CC2=O)(CC[C@]4(C)[C@@]5([H])C[C@@](C(OC)=O)(C)CC4)[C@]5(CC[C@]13C)C
Molecular Weight
464.64
References & Citations
[1]King AR, et al. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem Biol. 2009 Oct 30;16(10):1045-52.|[2]Deng Q, et al. Pristimerin inhibits angiogenesis in adjuvant-induced arthritic rats by suppressing VEGFR2 signaling pathways. Int Immunopharmacol. 2015 Dec;29(2):302-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1937/Pristimerin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1937/Pristimerin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1258-84-0
Available Sizes
Curated Selection
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