Pristimerin

Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.

Product Specifications

CAS Number

[1258-84-0]

Product Name Alternative

Celastrol methyl ester

UNSPSC

12352211

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Pristimerin.html

Purity

99.81

Solubility

DMF : 25 mg/mL (ultrasonic) |DMSO : 20 mg/mL (ultrasonic)

Smiles

C[C@](C1=CC=C(C(C)=C2O)C3=CC2=O)(CC[C@]4(C)[C@@]5([H])C[C@@](C(OC)=O)(C)CC4)[C@]5(CC[C@]13C)C

Molecular Formula

C30H40O4

Molecular Weight

464.64

References & Citations

[1]King AR, et al. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem Biol. 2009 Oct 30;16 (10) :1045-52.|[2]Deng Q, et al. Pristimerin inhibits angiogenesis in adjuvant-induced arthritic rats by suppressing VEGFR2 signaling pathways. Int Immunopharmacol. 2015 Dec;29 (2) :302-13.