VIRMA Recombinant Rabbit Monoclonal Antibody [PSH08-28]

Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA).

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

DKFZp434I116 antibody DKFZp781B2117 antibody fSAP121 antibody KIAA1429 antibody MGC138493 antibody MGC141940 antibody MSTP054 antibody Protein virilizer homolog antibody VIR_HUMAN antibody

Abbreviation

Protein virilizer homolog, VIRMA, KIAA1429, MSTP054

Swiss Prot

Q69YN4 Human,

Cellular Locus

Nucleus speckle, Nucleus, nucleoplasm, Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat,Monkey

Immunogen

Recombinant protein within human VIRMA aa 1,431-1,730.

Isotype

IgG

Clone

PSH08-28

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC, IP

Positive Control

K-562 cell lysate, MCF7 cell lysate, HeLa cell lysate, PC-3 cell lysate, T-47D cell lysate, SK-OV-3 cell lysate, COS-1 cell lysate, PC-12 cell lysate, C6 cell lysate, HeLa, PC-12, human colon cancer tissue, human stomach tissue, human testis tissue, rat stomach tissue, rat testis tissue.