CNT2 inhibitor-1
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2.
Product Specifications
CAS Number
880155-70-4
UNSPSC
12352005
Hazard Statement
H302
Target
Nucleoside Transporters
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/CNT2_inhibitor-1.html
Purity
98.77
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@H]([C@H]([C@H](N2C(NCC3=CC=C(C4=CC=CC=C4)C=C3)=NC5=C2N=CN=C5N)O1)O)O
Molecular Formula
C23H24N6O4
Molecular Weight
448.47
Precautions
H302
References & Citations
[1]Tatani K, et al. Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett. 2015 Jan 28;6 (3) :244-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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