14-epi-Andrographolide
14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent[1][2][3].
Product Specifications
Product Name Alternative
14-Epiandrographolide
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/14-epi-andrographolide.html
Smiles
C[C@]12[C@@](CCC([C@H]2C/C=C3[C@H](COC\3=O)O)=C)([H])[C@@](C)([C@@H](CC1)O)CO
Molecular Formula
C20H30O5
Molecular Weight
350.45
References & Citations
[1]MATSUDA T, et al. Cell differentiation-inducing diterpenes from Andrographis paniculata Nees[J]. Chemical and Pharmaceutical Bulletin, 1994, 42 (6) : 1216-1225.|[2]Gupta S, et al. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2017 Mar;162 (3) :611-623.|[3]Zhai ZJ, et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171 (3) :663-75.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0191A/14-epi-Andrographolide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0191A/
Scientific Category
Natural Products
Clinical Information
No Development Reported
CAS Number
[142037-79-4]
Available Sizes
Curated Selection
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