14-epi-Andrographolide

14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent[1][2][3].

Product Specifications

CAS Number

[142037-79-4]

Product Name Alternative

14-Epiandrographolide

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/14-epi-andrographolide.html

Smiles

C[C@]12[C@@](CCC([C@H]2C/C=C3[C@H](COC\3=O)O)=C)([H])[C@@](C)([C@@H](CC1)O)CO

Molecular Formula

C20H30O5

Molecular Weight

350.45

References & Citations

[1]MATSUDA T, et al. Cell differentiation-inducing diterpenes from Andrographis paniculata Nees[J]. Chemical and Pharmaceutical Bulletin, 1994, 42 (6) : 1216-1225.|[2]Gupta S, et al. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2017 Mar;162 (3) :611-623.|[3]Zhai ZJ, et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171 (3) :663-75.