Anhydronotoptol
Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibits NO production in RAW 264.7 cells induced by LPS with an IC50 value of 36.6 μM[1].
Product Specifications
CAS Number
[88206-51-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anhydronotoptol.html
Solubility
10 mM in DMSO
Smiles
CC(/C=C/C/C(C)=C/COC1=C(C=CO2)C2=CC(O3)=C1C=CC3=O)=C
Molecular Formula
C21H20O4
Molecular Weight
336.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Xikang Zheng, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum. Fitoterapia. 2018 Nov;131:65-72.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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