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3′-O-N3-dATP

3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm-1, which determines the DNA sequences continuously[1].

Product Specifications

CAS Number

1048021-78-8

Product Name Alternative

3′-O-Azidomethyl dATP

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Oligonucleotides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-o-n3-datp.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](OCN=[N+]=[N-])C3

Molecular Formula

C11H17N8O12P3

Molecular Weight

546.22

References & Citations

[1]Palla M, et al., DNA sequencing by synthesis using 3'-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection. RSC Adv. 2014 Jan 1;4 (90) :49342-49346.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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