Dexmedetomidine (Standard)

Dexmedetomidine (Standard) is the analytical standard of Dexmedetomidine. This product is intended for research and analytical applications. Dexmedetomidine ((+) -Medetomidine) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine exhibits anxiolysis, sedation, and modest analgesia effects[1][2][3].

Product Specifications

CAS Number

[113775-47-6]

Product Name Alternative

(+) -Medetomidine (Standard) ; (S) -Medetomidine (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/dexmedetomidine-standard.html

Purity

99.92

Smiles

C[C@H](C1=CN=CN1)C2=CC=CC(C)=C2C

Molecular Formula

C13H16N2

Molecular Weight

200.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Virtanen R, et, al. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol. 1988 May 20;150 (1-2) :9-14.|[2]Gertler R, et, al. Dexmedetomidine: a novel sedative-analgesic agent. Proc (Bayl Univ Med Cent) . 2001 Jan;14 (1) :13-21.|[3]Sajid B, et, al. A comparison of oral dexmedetomidine and oral midazolam as premedicants in children. J Anaesthesiol Clin Pharmacol. Jan-Mar 2019;35 (1) :36-40.