(S, S, R) -AHPC-C6-NH2 (hydrochloride)
(S, S, R) -AHPC-C6-NH2 hydrochloride is the E3 ligase ligand-linker conjugate, which can be utilized for synthesis of PROTAC HL-8.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-s-r-ahpc-c6-nh2-hydrochloride.html
Purity
97.20
Smiles
NCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O.[H]Cl
Molecular Formula
C29H44ClN5O4S
Molecular Weight
594.21
References & Citations
[1]Wang H, et al. Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase. Bioorg Med Chem. 2022 May 1;61:116707.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040226-500 1x 500 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741231-100 1x 100 µL
Eosinophil Peroxidase (AHE-1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881832-500 1x 500 µL
Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681858-100 1x 100 µL
CD43 (T-Cell Marker) (rSPN/1094), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details