SB 207710
SB 207710 is a highly selective antagonist of the 5-HT4 receptor that has been shown to effectively block the positive inotropic effect induced by serotonin in human right atrial appendage preparations[1].
Product Specifications
CAS Number
148703-08-6
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sb-207710.html
Smiles
O=C(OCC1CCN(CC1)CCCC)C2=C3OCCOC3=C(C(I)=C2)N
Molecular Formula
C19H27IN2O4
Molecular Weight
474.33
References & Citations
[1]Kaumann A J, et al. Blockade of human atrial 5-HT 4 receptors by SB 207710, a selective and high affinity 5-HT 4 receptor antagonist[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1994, 349: 546-548.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog