L-6355
L-6355 is an Amiodarone (HY-14187) related compound, which inhibits Ca2+/calmodulin activated cyclic nucleotide phosphodiesterase with an IC50 value of 0.65 μM. L-6355 is promising for research of antiarrhythmic and antianginal agent[1].
Product Specifications
CAS Number
[85642-08-6]
UNSPSC
12352005
Hazard Statement
H315-H319-H335-H351-H361-H362-H400-H410
Target
Calmodulin; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-6355.html
Smiles
O=C(C1=C(CCCC)OC2=C1C=CC=C2)C3=CC=C(C(I)=C3)OCCN(CC)CC
Molecular Formula
C25H30INO3
Molecular Weight
519.42
Precautions
P260-P263-P264-P270-P271-P273-P280-P302+P352-P305+P351+P338-P362-P391-P403+P233-P405-P501
References & Citations
[1]Nokin P, et al. Amiodarone is a potent calmodulin antagonist. Naunyn Schmiedebergs Arch Pharmacol. 1989 Apr;339 (4) :367-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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