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L-6355

L-6355 is an Amiodarone related compound, which inhibits Ca2+/calmodulin activated cyclic nucleotide phosphodiesterase with an IC50 value of 0.65 μM. L-6355 is promising for research of antiarrhythmic and antianginal agent[1].

Product Specifications

CAS Number

85642-08-6

UNSPSC

12352005

Hazard Statement

H315-H319-H335-H351-H361-H362-H400-H410

Target

Calmodulin; Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-6355.html

Smiles

O=C(C1=C(CCCC)OC2=C1C=CC=C2)C3=CC=C(C(I)=C3)OCCN(CC)CC

Molecular Formula

C25H30INO3

Molecular Weight

519.42

Precautions

P260-P263-P264-P270-P271-P273-P280-P302+P352-P305+P351+P338-P362-P391-P403+P233-P405-P501

References & Citations

[1]Nokin P, et al. Amiodarone is a potent calmodulin antagonist. Naunyn Schmiedebergs Arch Pharmacol. 1989 Apr;339 (4) :367-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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