Hnps-PLA-IN-1
Hnps-PLA-IN-1 (compound 5aa), a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM) [1].
Product Specifications
CAS Number
[185298-58-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hnps-pla-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=C(CC)N(CC2=CC=CC=C2)C3=C1C(OCC(N)=O)=CC=C3)=O)N
Molecular Formula
C21H21N3O4
Molecular Weight
379.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Draheim SE, et al. Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. J Med Chem. 1996 Dec 20;39 (26) :5159-75.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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