YM-17690
YM-17690 is a LTD4 and LTE4 agonist, with a pKi value of 9.28 for [3H]LTD4. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16, 3.9, and 22 nM, respectively. YM-17690 can be used in research related to asthma and inflammation[1].
Product Specifications
CAS Number
108806-41-3
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ym-17690.html
Smiles
O=C(O)CCC1=CC=C(OCC(O)=O)C(NC(C2=CC=C(OCCCCC3=CC=CC=C3)C=C2)=O)=C1
Molecular Formula
C28H29NO7
Molecular Weight
491.53
References & Citations
[1]Tomioka K, et al. Isolated tissue and binding studies of YM-17690, a novel and non-analogous leukotriene agonist. J Pharm Pharmacol. 1987 Oct;39 (10) :819-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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