HPK1-IN-47
HPK1-IN-47 is a HPK1 ligand. HPK1-IN-47 can be used for synthesis of PROTACs, such as PROTAC HPK1 Degrader-2. HPK1-IN-47 can be used for research of HPK1-mediated diseases including cancer[1].
Product Specifications
CAS Number
2893885-42-0
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-47.html
Smiles
CC1=C2C(CCNC2)=CC(C3=NC(C(C4=CC=C(C(N(C)C)=O)C(C)=C4)=CN5)=C5N=C3)=C1
Molecular Formula
C26H27N5O
Molecular Weight
425.53
References & Citations
[1]Sanjia XU, et al. PYRROLO [2, 3-b] PYRAZINE-BASED BIFUNCTIONAL COMPOUNDS AS HPK1 DEGRADERS AND THE USE THEREOF. Patent. WO2023006063.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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