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Fluvastatin (sodium) (Standard)

Fluvastatin (sodium) (Standard) is the analytical standard of Fluvastatin (sodium) . This product is intended for research and analytical applications. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].

Product Specifications

CAS Number

93957-55-2

Product Name Alternative

XU 62-320 (Standard)

UNSPSC

12352005

Target

Autophagy; Ferroptosis; HMG-CoA Reductase (HMGCR) ; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/fluvastatin-sodium-standard.html

Smiles

O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3

Molecular Formula

C24H25FNNaO4

Molecular Weight

433.45

References & Citations

[1]Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213 (2) :377-84.|[2]Wu Zhang, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48 (12) :1167-74.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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