4'-Methylchrysoeriol

4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.

Product Specifications

CAS Number

[4712-12-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4_acute_-Methylchrysoeriol.html

Purity

99.17

Solubility

DMSO : 20.83 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C17H14O6

Molecular Weight

314.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22 (7) :1325-33.