5-Bromocytosine
5-Bromocytosine is a Cytosine derivative. 5-Bromocytosine can be incorporated into cellular DNA and promote DNA chain breakage and cross-linking under ultraviolet irradiation[1][2].
Product Specifications
CAS Number
2240-25-7
UNSPSC
12352200
Hazard Statement
H302, H315, H317, H318, H335
Target
DNA Alkylator/Crosslinker; Drug Derivative
Type
Biochemical Assay Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-amino-5-bromopyrimidin-2-1h-one.html
Concentration
10mM
Purity
99.90
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C1N=C(C(Br)=CN1)N
Molecular Formula
C4H4BrN3O
Molecular Weight
190.00
Precautions
H302, H315, H317, H318, H335
References & Citations
[1]Aschi M, et al. A Combined Experimental and Computational Study of Halogen and Hydrogen Bonding in Molecular Salts of 5-Bromocytosine. Molecules. 2021 May 23;26 (11) :3111. |[2]Taguchi H, et al. Bromination of cytosine derivatives. The Journal of Organic Chemistry, 1979, 44 (24) : 4385-4393.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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