DGKζ-IN-7
DGKζ-IN-7 (compound 97) is an oral active DGKζ inhibitor with the IC50 of 33.4 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases[1].
Product Specifications
CAS Number
3058006-33-7
UNSPSC
12352005
Target
DGK; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dgkζ-in-7.html
Smiles
O=C(C(C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(S(F)(F)(F)(F)F)C=C3)=O)S2)N
Molecular Formula
C19H16F6N4O2S2
Molecular Weight
510.48
References & Citations
[1]Xie Yuli, et al. Thiazole compounds as DGKζ inhibitors. China, WO2024208198A1. 2024-10-10
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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