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Cynomolgus Tau Protein, Tag Free

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Product Specifications

Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Specifications

This protein carries no "tag". The protein has a calculated MW of 82.9 kDa.

Accession Number

A0A2K5WB98-1

Expression Region

Ala 2 - Leu 776

Host

Yeast

Target

Tau

Conjugation

Unconjugated

Tag

Native

Source

Cynomolgus

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.1 EU per μg

Purity

85%

Bioactivity

Immobilized Cynomolgus Tau Protein, Tag Free (Cat. No. TAU-C5113) at 5 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.1-8 ng/mL (QC tested).

Format

Powder

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

82.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

Yeast

Species

Cynomolgus

Protein ID

A0A2K5WB98-1

Preservative

Trehalose

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