17-Phenyl-ω-trinor-PGE2
17-Phenyl-ω-trinor-PGE2 is a PGE2 (HY-101952) analog, which is an agonist for EP1 and EP3 receptor. 17-Phenyl-ω-trinor-PGE2 inhibits the PAF-induced aggregation of human platelet-rich plasma (PRP) and Cicaprost (HY-19583) induced Cyclic AMP (HY-B1511) production[1].
Product Specifications
CAS Number
[38315-43-4]
UNSPSC
12352005
Hazard Statement
H302, H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/17-phenyl-ω-trinor-pge2.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)CC1=O
Molecular Formula
C23H30O5
Molecular Weight
386.48
Precautions
H302, H360
References & Citations
[1]Matthews JS, et al., Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues. Br J Pharmacol. 1993 Feb;108 (2) :363-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP
Available Sizes
Curated Selection
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