JPC0323 Oleate
JPC0323 Oleate is a derivative of JPC0323. JPC0323 is a dual 5-HT2C/5-HT2A receptor positive allosteric modulator. JPC0323 has on-target properties, acceptable plasma exposure and brain penetration. JPC0323 can be used for the research of neurological disease[1].
Product Specifications
CAS Number
1612785-68-8
UNSPSC
12352211
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/jpc0323-oleate.html
Smiles
CCCCCCCC/C=C\CCCCCCCC(OCC(CO)(CO)NC(CCCCCCC/C=C\CCCCCCCC)=O)=O
Molecular Formula
C40H75NO5
Molecular Weight
650.03
References & Citations
[1]Chen J, et al. Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT2C Receptor and Dual 5-HT2C/5-HT2A Receptor Modulators. J Med Chem. 2023 Jul 27;66 (14) :9992-10009.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
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