Minesapride
Minesapride is a partial agonist with a highly selective serotonin 4 (5-HT4) receptor. Minesapride enhances gastrointestinal peristalsis and colon transport by activating the 5-HT4 receptor. Minesapride increases bowel movements and suppresses visceral allergic reactions. Minesapride can be used in the study of constipation-type irritable bowel syndrome (IBS-C) [1].
Product Specifications
CAS Number
[1184662-54-1]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/minesapride.html
Smiles
OCC(N(CC1)CCC1CN(CCO2)C[C@@H]2CNC(C3=C(C=C(C(Cl)=C3)N)OC)=O)=O
Molecular Formula
C21H31ClN4O5
Molecular Weight
454.95
References & Citations
[1]Fukudo S, et al. Efficacy and safety of 5-HT4 receptor agonist minesapride for irritable bowel syndrome with constipation in a randomized controlled trial[J]. Clinical Gastroenterology and Hepatology, 2021, 19 (3) : 538-546. e8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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