5-BrdU
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
Product Specifications
CAS Number
59-14-3
Product Name Alternative
BrdU; 5-Bromo-2'-deoxyuridine; BUdR
UNSPSC
12352005
Hazard Statement
H340, H361
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-BrdU.html
Purity
99.97
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1C[C@H](N2C(NC(C(Br)=C2)=O)=O)O[C@@H]1CO
Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10
Precautions
H340, H361
References & Citations
[1]Levkoff LH, et al. Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Neoplasia. 2008 Aug;10 (8) :804-16.|[2]Rothaeusler K, et al. Assessment of cell proliferation by 5-bromodeoxyuridine (BrdU) labeling for multicolor flow cytometry. Curr Protoc Cytom. 2007 Apr; Chapter 7:Unit7.31
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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