Me- (S, R, S) -AHPC-CO-CH2-Br
Me- (S, R, S) -AHPC-CO-CH2-Br is an E3 ligase ligand-linker conjugate. Me- (S, R, S) -AHPC-CO-CH2-Br can be used to synthesize JNJ-1013.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/me-s-r-s-ahpc-co-ch2-br.html
Smiles
BrCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)=O)=O
Molecular Formula
C25H33BrN4O4S
Molecular Weight
565.52
References & Citations
[1]Fu L, et al. Discovery of highly potent and selective IRAK1 degraders to probe scaffolding functions of IRAK1 in ABC DLBCL[J]. Journal of Medicinal Chemistry, 2021, 64 (15) : 10878-10889.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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