(E) -GW7604
(E) -GW7604 is the (E) -isomer of GW7604, an antiestrogen and a metabolite of GW5638 , which is a high-affinity estrogen receptor (ER) antagonist[1].
Product Specifications
CAS Number
195611-82-6
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/e-gw7604.html
Smiles
CC/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)O)/C3=CC=C(C=C3)/C=C/C(O)=O
Molecular Formula
C25H22O3
Molecular Weight
370.44
References & Citations
[1]Willson TM, et al. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 1997 Sep;138 (9) :3901-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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